In late 2007, the eyes of the world were drawn to the Italian city of Perugia for the gruesome murder of a foreign exchange student and twisted tales of sex games gone wrong that emerged from its picturesque facade of steep mountain streets and centuries-old buildings.

Meredith Kercher, a 21-year-old from Surrey, England, had been sexually assaulted and stabbed to death, with her 20-year-old American roommate, Amanda Knox, and Knox’s boyfriend, Raffaele Sollecito, emerging as primary suspects. Although all conclusive physical evidence pointed elsewhere, Italian prosecutors focused on the alleged wrongdoings of the University of Washington student, whose MySpace nickname of “Foxy Knoxy” spawned countless stories of her being a promiscuous man-eater.